产品展示更多>>
- Rabbit anti-TRPM2 Polyclonal Antibody

- Rabbit anti-TRPM2 Polyclonal Antibody
Rabbit anti-TRPM2 Polyclonal Antibody
产品描述 别名 TRPM2抗体;KNP3; EREG1; TRPC7; LTRPC2; NUDT9H; LTrpC-2; NUDT9L1; TRPM2,TRPM2宿主 Rabbit反应种属 Mouse, Rat应用 WB:1:100-1:500, IF/ICC:1:50-1:100, ELISA:Recommended starting concentration is 1 μg/mL.分子量 Detects a band of approximately 171kDa (Predicted molecular weight171kDa)免疫原 Recombinant fusion protein containing a sequence corresponding to amino acids 1204-1503 of human TRPM2 (NP_003298.1).储存/保存方法 Store at -20℃. Avoid freeze / thaw cycles.存储溶液 PBS with 0.02% sodium azide,50% glycerol,pH7.3.性能 形式 Liquid纯化方法 Affinity purification类型 Polyclonal Antibody同种型 IgG标记 Unlabeled修饰 Unmodified靶标 背景说明 The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known.细胞定位 Membrane,Multi-pass membrane proteinUniProt O94759
实验结果图研究领域 研究领域 MetabolismPathways and ProcessesRedox metabolismOxidative stressNeuroscienceProcessesSignal TransductionSignaling PathwayCalcium SignalingCalcium ChannelsSignal TransductionSignaling PathwayCalcium SignalingOtherWestern blot analysis of lysates from Mouse lung, using TRPM2 Rabbit pAb at 1:500 dilution.|Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10000 dilution.|Lysates/proteins: 25μg per lane.|Blocking buffer: 3% nonfat dry milk in TBST.|Detection: ECL Enhanced Kit .|Exposure time: 90s.Immunofluorescence analysis of paraffin-embedded rat brain using TRPM2 Rabbit pAb at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.Immunofluorescence analysis of paraffin-embedded mouse brain using TRPM2 Rabbit pAb at dilution of 1:100. Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) at 1:500 dilution. Blue: DAPI for nuclear staining.Rabbit anti-TRPM2 Polyclonal Antibody温馨提示:本产品仅作科研实验使用,不支持临床等研究



