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- IL-2RB/CD122 （C-6His）
- IL-2RB/CD122 （C-6His）
概述 描述 Recombinant Human IL-2 receptor beta is produced by our Mammalian expression system and the target gene encoding Ala27-Asp239 is expressed with a 6His tag at the C-terminus. 别名 Interleukin-2 receptor subunit beta,IL2RB,IL-2 receptor subunit beta,IL-2R subunit beta,High affinity IL-2 receptor subunit beta,CD122 形态 Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4. 来源 Human Cells 氨基酸序列 AVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILG APDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQ ASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWS PWSQPLAFRTKPAALGKDVDHHHHHH 内毒素水平 Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test. Accession # P14784 性能 背景 Human IL-2RB, also known asinterleukin-2 receptor subunit beta,is the receptor for interleukin-2. IL2 receptor complex is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2 receptor complex has three forms with respect to ability to bind IL2. IL-2RB is belonged to a type I membrane protein,and has a 26 residue signal peptide, a 214 residue extracellular region, a 25 residue transmembrane region and a 286 residue cytoplasmic domain. IL-2RB is the subunit critical for receptor-mediated signaling via physically or functionally coupling to other signaling molecules, such as the Jak-STAT and Src-family protein tyrosine kinase although it lacks apparent catalytic motifs. 溶解方法 Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 保存方法 Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. 纯度 Greater than 95% as determined by reducing SDS-PAGE.