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- DNQX 2379-57-9
- DNQX 2379-57-9
DNQX 2379-57-9
产品描述 描述 DNQX is a non-N-methyl-D-aspartate (non-NMDA) receptor complex antagonist. The compound has been shown to attenuate JNK3 activation and has been shown not to stimulate a robust long-term potentiation in hippocampul studies. 6,7-Dinitroquinoxaline-2,3-dione (DNQX) is an inhibitor of GluR.
应用 A non-NMDA receptor complex antagonist纯度 98%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 FG 9041;6,7-Dinitroquinoxaline-2,3-dione外观 Pale yellow solid可溶性/溶解性 DMSO: ≥ 35 mg/mL.生物活性 靶点 iGluR参考文献 参考文献 [1]. Watkins JC et al. Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitive antagonists. Trends Pharmacol Sci. 1990 Jan;11(1):25-33.
[2]. Honoré T et al. Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science. 1988 Aug 5;241(4866):701-3.研究领域 研究领域 Drug DiscoverySmall Molecule DrugLead Compound DiscoveryDNQX 2379-57-9 温馨提示：本产品仅作科研实验使用，不支持临床等研究