Sabin Poliovirus Type I PAb, HRP-conjugated抗体;Sabin Poliovirus Type I

Guinea Pig

Sabin Polio virus

Sabin株脊髓灰质炎灭活病毒1型

Store at 4°C for 6 months. It is recommended to aliquote to ~10ul per vial and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.

0.1M PBS, PH 8.0, with protein stabilizer

1mg/ml

Dialysis after Labeling

Polyclonal Antibody

HRP

Unmodified

Poliovirus is structurally similar to other human enteroviruses (coxsackieviruses, echoviruses, and rhinoviruses), which also use immunoglobulin-like molecules to recognize and enter host cells. Phylogenetic analysis of the RNA and protein sequences of poliovirus suggests that it may have evolved from a C-cluster Coxsackie A virus ancestor, that arose through a mutation within the capsid. The distinct speciation of poliovirus probably occurred as a result of change in cellular receptor specificity from intercellular adhesion molecule-1 (ICAM-1), used by C-cluster Coxsackie A viruses, to CD155; leading to a change in pathogenicity, and allowing the virus to infect nervous tissue.