Sabin Poliovirus Type I PAb, HRP-conjugated抗体;Sabin Poliovirus Type I

Cow

Sabin Polio virus

Sabin株脊髓灰质炎灭活病毒1型

Store at 4°C for 6 months. It is recommended to aliquote to ~10ul per vial and store at -20°C for long term storage. Avoid repeated freezing and thawing cycles.

0.1M PBS, PH 8.0, with protein stabilizer

1mg/ml

Dialysis after Labeling

Polyclonal Antibody

HRP

Unmodified

Poliovirus infects human cells by binding to an immunoglobulin-like receptor, CD155, (also known as the poliovirus receptor (PVR)) on the cell surface. Interaction of poliovirus and CD155 facilitates an irreversible conformational change of the viral particle necessary for viral entry.Attached to the host cell membrane, entry of the viral nucleic acid was thought to occur one of two ways: via the formation of a pore in the plasma membrane through which the RNA is then “injected" into the host cell cytoplasm, or that the virus is taken up by receptor-mediated endocytosis.