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- Ebselen 20 mg
- Ebselen 20 mg
概述 描述 Ebselen is an interesting organoselenium compound displaying antiinflammatory and antioxidant properties. Ebselen is shown to inhibit the 5-lipoxygenase (5-LO) and 15-lipoxygenase (15-LO) enzymes in the absence of glutathione. Ebselen also inhibits Cox (cyclooxygenase), PKC (protein kinase C), DECR1 (NADPH), and Mox-1 (NADPH oxidase). The oxidation of low density lipoproteins by free radicals is suppressed by the antioxidant action of Ebselen. Ebselen is an inhibitor of Cox-1, Cox-2, NOS, GST and IDO. 别名 2-Phenyl-1,2-benzisoselenazol-3(2H)-one; Harmokisane; Ebselene 应用 An inhibitor of 5-LO, 15-LO, Cox, NADPH, and NADPH oxidase 性能 保存方法 Store at RT 纯度 ≥98% 分子量 274.18 溶解性 Soluble in PBS pH7.2, DMSO (25 mg/ml), ethanol (10 mg/ml), methanol, acetone, acetonitrile, and DMF (~5 mg/ml). CAS号 60940-34-3 外观 White solid 功能 inhibitor