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- Phosphoramidon Disodium Salt 164204-38-0;119942-99

- Phosphoramidon Disodium Salt 164204-38-0;119942-99
Phosphoramidon Disodium Salt 164204-38-0;119942-99-3
产品描述 描述 Phosphoramidon Disodium Salt is a metalloendopeptidase inhibitor, widely used as a biochemical tool.
纯度 98%储存/保存方法 Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.基本信息 可溶性/溶解性 DMSO :100 mg/mL (169.92 mM)生物活性 靶点 metalloendopeptidaseIn vitro(体外研究) Phosphoramidon is a powerful inhibitor of thermolysin without inhibiting the other endopeptidases such as trypsin, papain, chymotrypsin. Phosphoramidon reduces tumor cell invasion in CC531 cells.In vivo(体内研究) In rats bearing colon carcinoma CC531 xenografts, Phosphoramidon (250 mg/Rat i.p.) significantly reduces tumor cell growth. Intranasal phosphoramidon increases beta-amyloid levels in wild-type and NEP/NEP2-deficient mice, and thus can be use to model Alzheimer's disease (AD).参考文献 参考文献 研究领域 研究领域 NeuroscienceEndocrine systemDrug DiscoverySmall Molecule DrugLead Compound DiscoveryPhosphoramidon Disodium Salt 164204-38-0;119942-99-3温馨提示:本产品仅作科研实验使用,不支持临床等研究
