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- HJC0350 885434-70-8
- HJC0350 885434-70-8
HJC0350 885434-70-8
产品描述 描述 HJC0350 is a potent and selective EPAC2 inhibitor with IC50 of 0.3 μM, exhibiting no inhibition on Epac1.纯度 98%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 可溶性/溶解性 DMSO:52 mg/mL warmed (187.46 mM)生物活性 靶点 EPAC2In vitro(体外研究) HJC0350 selectively blocks cAMP-induced EPAC2 activation but do not inhibit cAMP-mediated PKA activation. In HEK293/EPAC2-FL cells, HJC0350 also inhibits 007-AM mediated cellular activation of EPAC2.参考文献 参考文献 1. Chen H, et al. J Med Chem. 2013, 56(3), 952-962.
研究领域 研究领域 Signal TransductionSecond MessengerNucleotide MessengercAMPSignal TransductionSecond MessengerNucleotide MessengercGMPDrug DiscoverySmall Molecule DrugLead Compound DiscoveryHJC0350 885434-70-8温馨提示：本产品仅作科研实验使用，不支持临床等研究