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- Pyridone 6 457081-03-7
- Pyridone 6 457081-03-7
Pyridone 6 457081-03-7
产品描述 描述 Pyridone 6(CMP 6) is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM) for other protein tyrosine kinases.
纯度 ＞98%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 吡啶酮6；CMP 6；JAK Inhibitor I可溶性/溶解性 DMSO : ≥ 31.25 mg/mL (101.02 mM)参考文献 参考文献 1. Nakagawa R, et al. J Immunol. 2011 Nov 1;187(9):4611-20.
研究领域 研究领域 Cell CycleKinases/PhosphatasesCdksEpigeneticsCell cycleKinases/PhosphatasesCdksImmunologyImmune System DiseasesAntiviral SignalingHIV-relatedMicrobiologyProteinHuman ProteinDefensinDrug DiscoverySmall Molecule DrugLead Compound DiscoveryPyridone 6 457081-03-7温馨提示：本产品仅作科研实验使用，不支持临床等研究