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- KRCA-0008 1472795-20-2

- KRCA-0008 1472795-20-2
KRCA-0008 1472795-20-2
产品描述 描述 KRCA-0008 is a potent and selective ALK/Ack1 inhibitor with IC50 of 12 nM/4 nM for ALK and Ack1 respectively; displays drug-like properties without hERG liability.纯度 99%储存/保存方法 Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.基本信息 可溶性/溶解性 10 mM in DMSO生物活性 靶点 Ack1参考文献 参考文献 1. Park CH, et al. Bioorg Med Chem Lett. 2013 Nov 15;23(22):6192-6.
研究领域 研究领域 CancerCell cycleKinases/phosphatasesOtherCancerGrowth factorsEGFEpigeneticsNuclear Signaling PathwaysNuclear ReceptorsTestosteroneSignal TransductionGrowth Factors/HormonesEGFSignal TransductionProtein PhosphorylationTyrosine KinasesOtherSignal TransductionSignaling PathwayG Protein SignalingSmall G ProteinsOtherDrug DiscoverySmall Molecule DrugLead Compound DiscoveryKRCA-0008 1472795-20-2温馨提示:本产品仅作科研实验使用,不支持临床等研究
