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- Cilastatin 82009-34-5
- Cilastatin 82009-34-5
Cilastatin 82009-34-5
产品描述 描述 A renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cilastatin is administered with imipenem to increase its effectiveness. The drug also inhibits the metabolism of leukotriene D4 to leukotriene E4.
纯度 99%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 西司他丁外观 类白色至黄白色固体可溶性/溶解性 DMSO : 15 mg/mL (41.85 mM; Need ultrasonic)参考文献 参考文献 1. Farrell CA, et al. Arch Biochem Biophys. 1987 Jul;256(1):253-9.
2. Kumon H, et al. Patients with renal insufficiency] Jpn J Antibiot. 1987 Sep;40(9):1571-83.
研究领域 研究领域 MetabolismTypes of diseaseDrug DiscoverySmall Molecule DrugLead Compound DiscoveryCilastatin 82009-34-5温馨提示：本产品仅作科研实验使用，不支持临床等研究