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- Flupenthixol 2HCl 51529-01-2

- Flupenthixol 2HCl 51529-01-2
Flupenthixol 2HCl 51529-01-2
产品描述 描述 Flupenthixol is a strong dopamine receptor antagonist.纯度 98%储存/保存方法 Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.基本信息 可溶性/溶解性 10 mM in DMSO生物活性 In vitro(体外研究) Flupenthixol, with its broad receptor profile, interacts with a variety of dopamine and serotonin binding sites which are important in the neurobiology of alcohol dependence. Flupenthixol antagonizes dopamine binding at a number of receptor subtypes, primarily at D1, D2, D3 and with less affinity at D4 receptors, and also affects serotonin binding at 5-HT2A and 5-HT2C receptors as well as noradrenaline binding at α1-adrenergic receptors.参考文献 参考文献 1. Dwivedi VS, et al. Curr Med Res Opin. 1990;12(3):191-7.
研究领域 研究领域 MetabolismTypes of diseaseObesityNeuroscienceProcessesNeuroscienceNeurotransmissionReceptors / ChannelsGPCRSerotonin ReceptorsDrug DiscoverySmall Molecule DrugLead Compound DiscoveryFlupenthixol 2HCl 51529-01-2温馨提示:本产品仅作科研实验使用,不支持临床等研究
