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- SKF-86002 72873-74-6
- SKF-86002 72873-74-6
SKF-86002 72873-74-6
产品描述 描述 SKF-86002 is a potent inhibitor of p38 MAP kinase wit IC50 of 0.5-1 uM; inhibits LPS-induced IL-1 and TNF-_alpha_ production in human monocytes (IC50 = 1 _mu_M).
纯度 98%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 SKF 86002外观 off-white solid可溶性/溶解性 DMSO >10mM生物活性 靶点 p38 MAPK参考文献 参考文献 1. Griswold DE, et al. Biochem Pharmacol. 1987 Oct 15;36(20):3463-70.
2. Frasch SC, et al. J Biol Chem. 1998 Apr 3;273(14):8389-97.
研究领域 研究领域 CancerSignal transductionProtein phosphorylationSerine/threonine kinasesMAPK pathwayDrug DiscoverySmall Molecule DrugLead Compound DiscoverySKF-86002 72873-74-6温馨提示：本产品仅作科研实验使用，不支持临床等研究