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- Tipiracil HCl 183204-72-0
- Tipiracil HCl 183204-72-0
Tipiracil HCl 183204-72-0
产品描述 描述 Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials纯度 98%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 可溶性/溶解性 10 mM in DMSO生物活性 靶点 Nucleoside Antimetabolite_AnalogIn vitro(体外研究) Tipiracil has antiangiogenic effect, and inhibits proliferation of endothelial cells. Tipiracil is a potent inhibitor of thymidine phosphorylase, which is the enzyme that degrades FTD.In vivo(体内研究) 参考文献 参考文献 1. Yoshino T, et al. Lancet Oncol. 2012 Oct;13(10):993-1001.
研究领域 研究领域 EpigeneticsDNA / RNADNA SynthesisOtherMetabolismPathways and ProcessesMetabolic signaling pathwaysNucleotide metabolismPurine and pyrimidine synthesisDrug DiscoverySmall Molecule DrugLead Compound DiscoveryTipiracil HCl 183204-72-0温馨提示：本产品仅作科研实验使用，不支持临床等研究