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- Endoxifen Z-isomer 112093-28-4
- Endoxifen Z-isomer 112093-28-4
Endoxifen Z-isomer 112093-28-4
产品描述 描述 Endoxifen is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ER_alpha_). Endoxifen inhibits hERG tail currents at 50 mV in a concentration-dependent manner with IC50 values of 1.6 uM.
纯度 98%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 Z-因多昔芬；(Z)-N-去甲基-4-羟基三苯氧胺外观 Off-White to Pale Red Solid可溶性/溶解性 10 mM in DMSO参考文献 参考文献 1. Chae YJ, et al. Eur J Pharmacol. 2015 Apr 5;752:1-7.
2. Wu X, et al. Breast Cancer Res. 2011 Mar 10;13(2):R27.
研究领域 研究领域 NeuroscienceEndocrine systemDrug DiscoverySmall Molecule DrugLead Compound DiscoveryEndoxifen Z-isomer 112093-28-4温馨提示：本产品仅作科研实验使用，不支持临床等研究