＞98%

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

硫酸双氢链mei素；Dihydrostreptomycin sesquisulfate

白色或类白色结晶性粉末

Water : 92 mg/mL (125.9 mM)

The primary mechanism of action of the antibiotic dihydrostreptomycin is binding to and modifying the function of the bacterial ribosome, thus leading to decreased and aberrant translation of proteins. It enters bacterial cells by binding to a specific site on MscL(mechanosensitive channel of large conductance) and modifying its conformation, thus allowing the passage of K+ and glutamate out of, and dihydrostreptomycin into, the cell.

Dihydrostreptomycin sulfate would cause cochlea damage in mouse model and cell proliferation in the spiral ligament may occur after the dihydrostreptomycin sulfate -induced damage. This process is probably related to the recovery of cochlear function.