- Wiskostatin 253449-04-6
- Wiskostatin 253449-04-6
Wiskostatin 253449-04-6
产品描述 描述 Wiskott-Aldrich syndrome protein (WASP) and WAVE stimulate actin-related protein (Arp)2/3-mediated actin polymerization, leading to diverse downstream effects, including the formation and remodeling of cell surface protrusions, modulation of cell migration, and intracytoplasmic propulsion of organelles and pathogens. Selective inhibitors of individual Arp2/3 activators would enable more exact dissection of WASP- and WAVE-dependent cellular pathways and are potential therapeutic targets for viral pathogenesis. Wiskostatin is a recently described chemical inhibitor that selectively inhibits neuronal WASP (N-WASP)-mediated actin polymerization in vitro.
纯度 98%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 1-(3,6-dibromocarbazol-9-yl)-3-(dimethylamino)propan-2-ol外观 white to beige powder可溶性/溶解性 10 mM in DMSO参考文献 参考文献 1. Guerriero CJ, Weisz OA. Am J Physiol Cell Physiol. 2007 Apr;292(4):C1562-6.
2. Bompard G, et al. BMC Cell Biol. 2008 Jul 30;9:42.
研究领域 研究领域 NeuroscienceDrug DiscoverySmall Molecule DrugLead Compound DiscoveryWiskostatin 253449-04-6温馨提示：本产品仅作科研实验使用，不支持临床等研究