PI-3065 is a novel potent and selective PI3K p110δ inhibitor with IC50 of 15 nM; exhibits > 100 fold selectivity against p110α, p110β, p110γ, DNA-PK and mTOR.

98%

Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.

PI3065

White to off white powder

DMSO : 25 mg/mL (49.34 mM; Need ultrasonic)

p110α；p110β；p110δ

PI-3065 exhibits no inhibition of the growth of 4T1 cells, which do not express detectable levels of p110δ.

PI-3065 (75 mg/kg, p.o.) inhibits the growth of 4T1 tumours in the BALB/c mice without obvious body weight loss.