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- Ilaprazole sodium 172152-50-0

- Ilaprazole sodium 172152-50-0
Ilaprazole sodium 172152-50-0
产品描述 描述 Ilaprazole is a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity. A weak base, ilaprazole accumulates in the acidic environment of the secretory canaliculus of the gastric parietal cell where it is converted to an active sulfenamide form that binds to cysteine sulfhydryl groups on the luminal aspect of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.纯度 98%储存/保存方法 Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.基本信息 可溶性/溶解性 Soluble in DMSO参考文献 参考文献 1. Seo KA, et al. Xenobiotica. 2012 Mar;42(3):278-84.
2. Bohidar NP, et al. Trop Gastroenterol. 2013 Apr-Jun;34(2):95-8.
研究领域 研究领域 CancerTumor biomarkersDrug DiscoverySmall Molecule DrugLead Compound DiscoveryIlaprazole sodium 172152-50-0温馨提示:本产品仅作科研实验使用,不支持临床等研究
