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- Adefovir dipivoxil 142340-99-6
- Adefovir dipivoxil 142340-99-6
Adefovir dipivoxil 142340-99-6
产品描述 描述 Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective against HIV-1. Adefovir dipivoxil is the diester prodrug of adefovir.
纯度 ＞98%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 阿德福韦；阿de福韦酯外观 白色或类白色粉末可溶性/溶解性 DMSO : 93 mg/mL (185.5 mM)
Ethanol : 93 mg/mL (185.5 mM)生物活性 靶点 Reverse transcriptaseIn vivo(体内研究) Adefovir Dipivoxil reduces Liver HBV DNA to参考文献 参考文献 1. Julander JG, et al. Antiviral Res, 2002, 55(1), 27-40.
2. Chien RN, Liaw YF. Best Pract Res Clin Gastroenterol. 2008;22(6):1081-92.
3. Delmas J, et al. Antimicrob Agents Chemother, 2002, 46(2), 425-433.
4. Kock J, et al. Hepatology. 2003 Dec;38(6):1410-8.
研究领域 研究领域 CancerDrug resistanceCancerTumor immunologyMetabolismTypes of diseaseDrug DiscoverySmall Molecule DrugLead Compound DiscoveryAdefovir dipivoxil 142340-99-6温馨提示：本产品仅作科研实验使用，不支持临床等研究