- Sulbactam 68373-14-8
- Sulbactam 68373-14-8
Sulbactam 68373-14-8
产品描述 描述 Sulbactam is a semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity.
纯度 99%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 舒巴坦；CP45899外观 白色或类白色结晶性粉末可溶性/溶解性
DMSO : 44 mg/mL (188.6 mM)
Ethanol : 44 mg/mL (188.6 mM)
Water : 43 mg/mL (184.4 mM)生物活性 靶点 β-Lactamase参考文献 参考文献 1. Singh GS, et al. Mini Rev Med Chem. 2004 Jan;4(1):93-109.
2. Totir MA, et al. Biochemistry. 2007 Aug 7;46(31):8980-7.
3. Lin CH, et al. Int J Antimicrob Agents. 2014 Jul;44(1):38-46.
研究领域 研究领域 MetabolismTypes of diseaseDrug DiscoverySmall Molecule DrugLead Compound DiscoverySulbactam 68373-14-8温馨提示：本产品仅作科研实验使用，不支持临床等研究