- Midodrine hydrochloride 3092-17-9
- Midodrine hydrochloride 3092-17-9
Midodrine hydrochloride 3092-17-9
产品描述 描述 Midodrine is converted to its active metabolite, desglymidodrine by deglycination reaction. Desglymidodrine selectively binds to and activates alpha-1-adrenergic receptors of the arteriolar and venous vasculature. This causes smooth muscle contraction and leads to an elevation of blood pressure. Desglymidodrine diffuses poorly across the blood-brain barrier and is therefore not associated with effects on the central nervous system. Midodrine Hydrochloride is the hydrochloride salt form of midodrine, a direct-acting prodrug and sympathomimetic agent with antihypotensive properties.
纯度 ＞98%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 盐suan米多君外观 白色结晶性粉末可溶性/溶解性 10 mM in DMSO生物活性 靶点 α-adrenergic receptor参考文献 参考文献 1. Buckner SA, et al. Eur J Pharmacol. 2002 Aug 2;449(1-2):159-65.
2. Taniguchi N, et al. Eur J Pharmacol. 1996 Dec 27;318(1):117-22.
3. Altenbach RJ, et al. J Med Chem. 2004 Jun 3; 47(12):3220-35.
研究领域 研究领域 Drug DiscoverySmall Molecule DrugLead Compound DiscoveryMidodrine hydrochloride 3092-17-9温馨提示：本产品仅作科研实验使用，不支持临床等研究