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- Etoricoxib 202409-33-4

- Etoricoxib 202409-33-4
Etoricoxib 202409-33-4
产品描述 描述 Etoricoxib(MK-0663) selectively inhibited COX-2 in human whole blood assays in vitro, with an IC50 value of 1.1 ± 0.1 μM for COX-2 (LPS-induced prostaglandin E2 synthesis), compared with an IC50 value of 116 ± 8 μM for COX-1 (serum thromboxane B2 generation after clotting of the blood).
纯度 99%储存/保存方法 Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.基本信息 别名 依托考昔;MK-663;MK-0663外观 类白色粉末可溶性/溶解性 DMSO : 66 mg/mL (183.9 mM)
Ethanol : 43 mg/mL (119.8 mM)参考文献 参考文献 1. Capone ML, et al. Prostaglandins Other Lipid Mediat. 2007 Jan;82(1-4):85-94.
2. Preissner S, et al. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43.
3. FitzGerald GA. Trends Pharmacol Sci. 2007 Jul;28(7):303-7. Epub 2007 Jun 18.
研究领域 研究领域 ImmunologyCancerTumor biomarkersDrug DiscoverySmall Molecule DrugLead Compound DiscoveryEtoricoxib 202409-33-4温馨提示:本产品仅作科研实验使用,不支持临床等研究
