- Cisatracurium besylate 96946-42-8
- Cisatracurium besylate 96946-42-8
Cisatracurium besylate 96946-42-8
产品描述 描述 Cisatracurium Besylate is a nondepolarizing skeletal muscle relaxant for intravenous administration. Cisatracurium Besylate acts on cholinergic receptors, blocking neuromuscular transmission. This action is antagonized by acetylcholinesterase inhibitors such as neostigmine. The neuromuscular block produced by cisatracurium besylate is readily antagonized by anticholinesterase agents once recovery has started. As with other nondepolarizing neuromuscular blocking agents, the more profound the neuromuscular block at the time of reversal, the longer the time required for recovery of neuromuscular function. Compared to other neuromuscular blocking agents, it is intermediate in its onset and duration of action.
纯度 ＞98%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 顺ben磺阿曲库铵；51W89外观 白色至淡黄色粉末可溶性/溶解性 DMSO : 229 mg/mL (184.2 mM)
Ethanol : 229 mg/mL (184.2 mM)
Water : 43 mg/mL (34.6 mM)生物活性 靶点 AChR, Adrenergic ReceptorIn vitro(体外研究) Cisatracurium Besylate (51W89) is a neuromuscular-blocking drug or skeletal muscle relaxant in the category of non-depolarizing neuromuscular-blocking drugs, used adjunctively in anesthesia to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. It is a bisbenzyltetrahydroisoquinolinium agent with an intermediate duration of action. Cisatracurium Besylate (51W89) is one of the ten isomers of the parent molecule, atracurium. Moreover, cisatracurium represents approximately 15% of the atracurium mixture.参考文献 参考文献 1. Dieye E, et al. Ann Intensive Care. 2014 Feb 11;4(1):3.
2. Szakmany T, Woodhouse T. Minerva Anestesiol. 2015 Apr; 81(4):450-60.
3. Dahaba AA, et al. Minerva Anestesiol. 2013 Nov; 79(11):1238-47.
研究领域 研究领域 NeuroscienceCancerCancer MetabolismDrug DiscoverySmall Molecule DrugLead Compound DiscoveryCisatracurium besylate 96946-42-8温馨提示：本产品仅作科研实验使用，不支持临床等研究