- Orphenadrine hydrochloride 341-69-5
- Orphenadrine hydrochloride 341-69-5
Orphenadrine hydrochloride 341-69-5
产品描述 描述 Orphenadrine is an anticholinergic drug of the ethanolamine antihistamine class with prominent central nervous system (CNS) and peripheral actions used to treat painful muscle spasms and other similar conditions, as well as the treatment of some aspects of Parkinson's disease. It is closely related to diphenhydramine. Therefore, it is related to other drugs used for Parkinson's, such as benztropine and trihexyphenidyl, and it is also structurally related to nefopam, which is a centrally acting yet nonopioid analgesic. The combination of anticholinergic effects and CNS penetration make orphenadrine useful for pain of all etiologies, including from: radiculopathy, muscles, and headaches
纯度 ＞98%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 盐酸奥芬那君；邻甲苯海拉明盐酸盐；奥芬那君盐酸盐外观 白色或类白色结晶性粉末可溶性/溶解性 10 mM in DMSO生物活性 靶点 H1 receptor,NMDA receptor,Noradrenaline transporter (Sodium-dependent),Sodium Channel参考文献 参考文献 1. Kornhuber J, et al. J Neural Transm Gen Sect. 1995;102(3):237-46.
2. Rumore MM, Schlichting DA. Life Sci. 1985 Feb 4;36(5):403-16.
3. Pubill D, et al. J Pharm Pharmacol. 1999 Mar;51(3):307-12.
4. Peng FC, Lin Wu SW. J Toxicol Environ Health A. 2002 Dec 27;65(24):2163-75.
5. Lin Wu SW, et al. J Toxicol Environ Health A. 2003 Mar 14; 66(5):453-67.
研究领域 研究领域 Drug DiscoverySmall Molecule DrugLead Compound DiscoveryOrphenadrine hydrochloride 341-69-5温馨提示：本产品仅作科研实验使用，不支持临床等研究