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- Triethylenethiophosphoramide 52-24-4

- Triethylenethiophosphoramide 52-24-4
Triethylenethiophosphoramide 52-24-4
产品描述 描述 Thiotepa is a polyfunctional, organophosphorus alkylating agent with antineoplastic activity.
纯度 >98%储存/保存方法 Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.基本信息 别名 三亚乙基硫代磷酰胺;Thio-TEPA外观 white solid可溶性/溶解性 DMSO : 91 mg/mL (480.9 mM)生物活性 靶点 DNA Alkylator_CrosslinkerIn vitro(体外研究) Thio-TEPA exhibits alkylating activity in rat liver slice incubation. Thio-TEPA does not affect the viability of rat liver slices, and is not accumulated in the slices at all doses of 2, 5, 10 mM.In vivo(体内研究) Thio-TEPA (20 mg/kg, i.p.) with total body irradiation (TBI) enhances donor-type blood chimerism during the first 10 weeks but is not dramatically higher than that of TBI group alone. Thio-TEPA alone improves both short- and long-term engraftment in mice.研究领域 研究领域 CancerCancer MetabolismCancerTumor biomarkersCancerTumor immunologyMetabolismTypes of diseaseDrug DiscoverySmall Molecule DrugLead Compound DiscoveryTriethylenethiophosphoramide 52-24-4温馨提示:本产品仅作科研实验使用,不支持临床等研究
