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- Sodium etidronate 7414-83-7
- Sodium etidronate 7414-83-7
Sodium etidronate 7414-83-7
产品描述 描述 Etidronate Disodium is a synthetic therapeutic diphosphonate analog of endogenous pyrophosphate. As a member of the family of drugs known as bisphosphonates, etidronate disodium differs from endogenous pyrophosphate in its resistance to enzymatic hydrolysis. This agent adsorbs to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting abnormal bone resorption. Etidronate may also directly stimulate bone formation by osteoblasts.
纯度 ＞98%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 依替膦酸钠；羟乙膦酸na外观 白色或黄色粉末可溶性/溶解性 Water : 11.5 mg/mL生物活性 靶点 protein tyrosine phosphatase参考文献 参考文献 1. Grases F, et al. Circ J. 2007 Jul; 71(7):1152-6.
2. Nancollas GH, et al. Bone. 2006 May;38(5):617-27.
3. Ono K, Wada S. Clin Calcium. 2004 Jun;14(6):60-3.
研究领域 研究领域 MetabolismCancerCancer MetabolismCancerTumor biomarkersDrug DiscoverySmall Molecule DrugLead Compound DiscoverySodium etidronate 7414-83-7
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