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- Acipimox 51037-30-0
- Acipimox 51037-30-0
Acipimox 51037-30-0
产品描述 描述 Acipimox is a niacin derivative used as a hypolipidemic agent. It is used in low doses and may have less marked adverse effects, although it is unclear whether the recommended dose is as effective as are standard doses of nicotinic acid. Acipimox inhibits the production of triglycerides by the liver and the secretion of VLDL, which leads indirectly to a modest reduction in LDL and increase in HDL. Long-term administration is associated with reduced mortality, but unwanted effects limit its clinical use.
纯度 99%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 阿西莫司；K-9321外观 白色或类白色粉末可溶性/溶解性 DMSO : 15.4 mg/mL (100 mM)
water : 15.4 mg/mL (100 mM)参考文献 参考文献 1. Jin F, et al. Biochem Biophys Res Commun. 2012 Nov 9; 428(1):86-92.
2. van de Weijer T, et al. Diabetes. 2015 Apr;64(4):1193-201.
3. Montecucco F, et al. Am J Physiol Endocrinol Metab. 2011 Apr; 300(4):E681-90.
研究领域 研究领域 Drug DiscoverySmall Molecule DrugLead Compound DiscoveryAcipimox 51037-30-0温馨提示：本产品仅作科研实验使用，不支持临床等研究