- (S)-(+)-Ketoprofen 22161-81-5

- (S)-(+)-Ketoprofen 22161-81-5
(S)-(+)-Ketoprofen 22161-81-5
产品描述 描述 Dexketoprofen works by blocking the action of a substance in the body called cyclo-oxygenase. It belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). Cyclo-oxygenase is involved in the production of chemicals in the body called prostaglandins. Prostaglandins are produced in response to injury or certain diseases and would otherwise go on to cause swelling, inflammation and pain. By blocking cyclo-oxygenase, dexketoprofen prevents the production of prostaglandins and therefore reduces inflammation and pain. Along with Peripheral analgesic action it possesses central analgesic action. Dexketoprofen is a non-steroidal anti-inflammatory drug. It is manufactured by Menarini, under the tradename Keral. It is available in the UK, as dexketoprofen trometamol, as a prescription-only drug and in Latin America as Miracox, produced by Stein in Costa Rica. In Italy it is available as an over the counter-drug under the tradename Enantyum. In Lithuania it is available as over the counter-drug uder tradename Dolmen.
纯度 99%储存/保存方法 Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.基本信息 别名 右旋酮luo芬;(S)-Ketoprofen;Dexketoprofen外观 白色结晶性粉末可溶性/溶解性 Water : 51 mg/L
DMSO : ≥ 125 mg/mL (491.58 mM)生物活性 靶点 COX-1,COX-2参考文献 参考文献 1. Pelligand L, et al. J Vet Pharmacol Ther. 2014 Aug;37(4):354-66.
2. Zhou SF, et al. Curr Med Chem. 2009; 16(27):3480-675.
3. Reid G, et al. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9244-9.
4. Shitara Y, et al. Pharm Res. 2002 Feb; 19(2):147-53.
5. Takeda M, et al. J Pharmacol Exp Ther. 2002 Aug; 302(2): 666-71.
研究领域 研究领域 ImmunologyDrug DiscoverySmall Molecule DrugLead Compound Discovery(S)-(+)-Ketoprofen 22161-81-5温馨提示:本产品仅作科研实验使用,不支持临床等研究
