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- Coumarin 91-64-5

- Coumarin 91-64-5
Coumarin 91-64-5
产品描述 描述 Extracted from Tonka bean,incense Liatris; Suitability:Alcohol,ether,chloroform,pyridine,volatile oil and alkali hydroxide solution;Store the product in sealed,cool and dry condition
纯度 >99%储存/保存方法 Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.基本信息 别名 香dou素外观 白色结晶性粉末可溶性/溶解性 DMSO : 28 mg/mL (191.6 mM)
Ethanol : 28 mg/mL (191.6 mM)生物活性 In vitro(体外研究) Coumarin is a fragrant organic chemical compound in the benzopyrone chemical class, which is a colorless crystalline substance in its standard state. Coumarin is a naturally occurring constituent of many plants and essential oils, including tonka beans, sweet clover, woodruff, oil of cassia, and lavender. Coumarin is a member of a class of compounds called benzopyrones. Coumarin compounds have been used to treat such diverse ailments as cancer, bums, brucellosis, and rheumatic disease, and they have been used as antispasmodics. Although coumarin itself has no anticoagulant properties, it is transformed into the natural anticoagulant dicoumarol by a number of species of fungi. This occurs as the result of the production of 4-hydroxycoumarin, then further into the actual anticoagulant dicoumarol, a fermentation product and mycotoxin. This substance is responsible for the bleeding disease known historically as "sweet clover disease" in cattle eating moldy sweet clover silage.参考文献 参考文献 1. Egan D, et al. Drug Metab Rev, 1990, 22(5), 503-529.
2. Akoudad S, et al. Stroke. 2014 Nov; 45(11):3436-9.
研究领域 研究领域 CancerTumor immunologyDrug DiscoverySmall Molecule DrugLead Compound DiscoveryCoumarin 91-64-5温馨提示:本产品仅作科研实验使用,不支持临床等研究
