产品展示更多>>
- Furazolidone 67-45-8
- Furazolidone 67-45-8
Furazolidone 67-45-8
产品描述 描述 Furazolidone is a nitrofuran derivative with antiprotozoal and antibacterial activity, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM.
纯度 99%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 呋喃zuo酮外观 淡黄色结晶性粉末可溶性/溶解性 DMSO > 10 mM生物活性 In vitro(体外研究) Furazolidone displays potent antiproliferative properties at submicromolar concentrations and induces apoptosis in AML cell lines. Furazolidone treatment of certain AML cells induces myeloid cell differentiation by morphology and flow cytometry for CD11b expression, resulting in increased stability of tumor suppressor p53 protein in AML cells.In vivo(体内研究) FZ accelerates its own metabolism in the chicken by induction of the activity of CPR whereas no effect is observed in the rat.参考文献 参考文献 1. Timperio AM, et al. Xenobiotica. 2003 Feb;33(2):153-67.
2. Ali BH. Vet Res Commun. 1999 Oct;23(6):343-60.
3. Hoogenboom LA, et al. Food Chem Toxicol. 1991 Mar;29(3):185-91.
研究领域 研究领域 CancerTumor immunologyMetabolismTypes of diseaseDrug DiscoverySmall Molecule DrugLead Compound DiscoveryFurazolidone 67-45-8温馨提示：本产品仅作科研实验使用，不支持临床等研究