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- Dibutyl phthalate 84-74-2
- Dibutyl phthalate 84-74-2
Dibutyl phthalate 84-74-2
产品描述 描述 Dibutyl phthalate is a plasticizer used in most plastics and found in water, air, soil, plants and animals. It may have some adverse effects with long-term exposure.
纯度 99%储存/保存方法 Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.基本信息 别名 邻苯二甲酸二丁酯外观 无色油状液体可溶性/溶解性 10 mM in DMSO生物活性 In vitro(体外研究) Dibutyl phthalate (0.001 µg/mL-1000 µg/mL) is detrimental to follicle growth and viability and results in significant dysregulation of cell cycle and apoptosis gene expression in a dose-specific manner. But MBP does not play a role in Dibutyl phthalate toxicity in follicles exposed in vitro.In vivo(体内研究)
Dibutyl phthalate (200, 400, or 600 mg/kg/day) induces decrease mice weight, impairment of spermatogenesis, reduces serum follicle stimulating hormone and testosterone level, alters testicular LDH, increases LPO, and decreases the levels of enzymatic antioxidants with histopathological anomalies.
Dibutyl phthalate (6.25, 12.5, 25, 50, 100 and 200 mg/kg) could cause some neurobehavioral adverse effects in mice.参考文献 参考文献 1. Euling SY, et al. Toxicol Appl Pharmacol. 2013 Sep 15;271(3):324-35.
1. Euling SY, et al. Toxicol Appl Pharmacol. 2013 Sep 15;271(3):324-35.
研究领域 研究领域 NeuroscienceCancerCancer MetabolismDrug DiscoverySmall Molecule DrugLead Compound DiscoveryDibutyl phthalate 84-74-2温馨提示：本产品仅作科研实验使用，不支持临床等研究