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- Erythromycin ethylsuccinate 1264-62-6

- Erythromycin ethylsuccinate 1264-62-6
Erythromycin ethylsuccinate 1264-62-6
产品描述 描述 Erythromycin Ethylsuccinate, an oral macrolide antibiotic produced by Streptomyces erythreus, reversibly binds to the 50S ribosome of bacteria, and inhibits protein synthesis.
纯度 98%储存/保存方法 Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.基本信息 别名 琥乙红mei素;Erythromycin ethyl succinate; EES外观 白色粉末可溶性/溶解性 DMSO : 158 mg/mL (183.3 mM)
Ethanol : 158 mg/mL (183.3 mM)生物活性 In vitro(体外研究) Erythromycin displays antibacterial activity against Staphylococcus aureus, streptococcus pneumonia, Streptococcus pyogenes, Haemophilus influenza, Moraxella catarrhalis, Bordetella pertussis, Neisseria gonorrhoeae, Campylobacter jejuni, Helicobacter pylori, and Borrelia burgdorferi. Erythromycin is a motilin receptor agonist, which is a potent stimulator of gastrointestinal motor activity. The concentrations of Erythromycin required to induce 50% of the maximum contractile response to a supramaximal dose of acetylcholine is 2 μM. The concentrations of Erythromycin required to displace 50% of the labeled motilin is 13 μM. Erythromycin has no effect on muscle strips of rat or dog duodenum but induces contractions in human strips.参考文献 参考文献 1. Halling SM, Jensen AE. BMC Microbiol. 2006 Oct 2;6:84.
2. Tu D, et al. Cell. 2005 Apr 22;121(2):257-70.
3. Cagliero C, et al. Antimicrob Agents Chemother. 2006 Nov;50(11):3893-6.
研究领域 研究领域 MetabolismTypes of diseaseDrug DiscoverySmall Molecule DrugLead Compound DiscoveryErythromycin ethylsuccinate 1264-62-6温馨提示:本产品仅作科研实验使用,不支持临床等研究
